➦   Mammalian Suppressor-of-Fused modulates nuclear–cytoplasmic shuttling of GLI-1

➦   Single-molecule analysis of kinesin motility reveals regulation by the cargo-binding tail domain

➦   Calcium signalling in cardiac muscle: refractoriness revealed by coherent activation

➦   VASP dynamics during lamellipodia protrusion

➦   An NSF function distinct from ATPase-dependent SNARE disassembly is essential for Golgi membrane fus

➦   The lectin ERGIC-53 is a cargo transport receptor for glycoproteins

➦   Formation of AP-3 transport intermediates requires Vps41 function

➦   Co-translational folding of an alphavirus capsid protein in the cytosol of living cells

➦   De novo generation of a PrPSc-like conformation in living cells

➦   Activation of a meiotic checkpoint regulates translation of Gurken during Drosophila oogenesis

➦   Identification of caveolin-1 in lipoprotein particles secreted by exocrine cells

➦   Rab5 regulates motility of early endosomes on microtubules

➦   Enteropathogenic E. coli acts through WASP and Arp2/3 complex to form actin pedestals

➦   Selective transport of internalized antigens to the cytosol for MHC class I presentation in dendriti

➦   Cholesterol modulates membrane traffic along the endocytic pathway in sphingolipid-storage diseases

➦   Identification of the natural ligand of an orphan G-protein-coupled receptor involved in the regulat

➦   Calponin modulates the exclusion of Otx-expressing cells from convergence extension movements

➦   A Rad3–Rad26 complex responds to DNA damage independently of other checkpoint proteins

➦   A new function for CD38/ADP-ribosyl cyclase in nuclear Ca2+ homeostasis

➦   Speckle microscopic evaluation of microtubule transport in growing nerve processes

➦   Evidence for a COP-I-independent transport route from the Golgi complex to the endoplasmic reticulum

➦   G1-phase and B-type cyclins exclude the DNA-replication factor Mcm4 from the nucleus

➦   The structural basis for specificity of substrate and recruitment peptides for cyclin-dependent kina

➦   Maternal Pumilio acts together with Nanos in germline development in Drosophila embryos

➦   Selective transfer of endogenous metabolites through gap junctions composed of different connexins

➦   Drosophila Lissencephaly-1 functions with Bic-D and dynein in oocyte determination and nuclear posit

➦   Engulfment of apoptotic cells involves the redistribution of membrane phosphatidylserine on phagocyt

➦   Modulation of phagosome biogenesis by Legionella pneumophila creates an organelle permissive for int

➦   Pleiotropic cell-division defects and apoptosis induced by interference with survivin function

➦   Coordination of calcium signalling by endothelial-derived nitric oxide in the intact liver

➦   Presenilin-1 mutations downregulate the signalling pathway of the unfolded-protein response

➦   Ubiquitin-dependent degradation of TGF-β-activated Smad2

➦   Cooperative symmetry-breaking by actin polymerization in a model for cell motility

➦   CUL-2 is required for the G1-to-S-phase transition and mitotic chromosome condensation in Caenorhabd

➦   Cell-autonomous regulation of cell and organ growth in Drosophila by Akt/PKB

➦   Melanoma chondroitin sulphate proteoglycan regulates cell spreading through Cdc42, Ack-1 and p130cas

➦   The yeast phosphatidylinositol-4-OH kinase Pik1 regulates secretion at the Golgi

➦   Components of the spindle-assembly checkpoint are essential in Caenorhabditis elegans

➦   Human homologue of S. pombe Rad9 interacts with BCL-2/BCL-xL and promotes apoptosis

➦   Rotation and asymmetry of the mitotic spindle direct asymmetric cell division in the developing cent

➦   A genetically encoded, fluorescent indicator for cyclic AMP in living cells

➦   Control of microtubule dynamics by the antagonistic activities of XMAP215 and XKCM1 in Xenopus egg e

➦   δ-Tubulin and ɛ-tubulin: two new human centrosomal tubulins reveal new aspects of centrosome structu

➦   Dynactin increases the processivity of the cytoplasmic dynein motor

➦   Cholesterol binds to synaptophysin and is required for biogenesis of synaptic vesicles

➦   The polarity and dynamics of microtubule assembly in the budding yeast Saccharomyces cerevisiae

➦   Peroxisomes in human fibroblasts have a basic pH

➦   Spindle assembly in Drosophila neuroblasts and ganglion mother cells

➦   Activation of EphA2 kinase suppresses integrin function and causes focal-adhesion-kinase dephosphory

➦   Chromaffin-cell stimulation triggers fast millimolar mitochondrial Ca2+ transients that modulate sec