➦   Quantal release of free radicals during exocytosis of phagosomes

➦   Dissecting the link between stress fibres and focal adhesions by CALI with EGFP fusion proteins

➦   Deregulated human Cdc14A phosphatase disrupts centrosome separation and chromosome segregation

➦   Identification of a link between the tumour suppressor APC and the kinesin superfamily

➦   Nucleotide exchange factor GEF-H1 mediates cross-talk between microtubules and the actin cytoskeleto

➦   Frodo interacts with Dishevelled to transduce Wnt signals

➦   Ras signalling on the endoplasmic reticulum and the Golgi

➦   Par-1 regulates stability of the posterior determinant Oskar by phosphorylation

➦   The TRPM7 channel is inactivated by PIP2 hydrolysis

➦   A new nuclear component of the Wnt signalling pathway

➦   A distinct class of endosome mediates clathrin-independent endocytosis to the Golgi complex

➦   Dysfunction of store-operated calcium channel in muscle cells lacking mg29

➦   E2F-dependent accumulation of hEmi1 regulates S phase entry by inhibiting APCCdh1

➦   Epsins and Vps27p/Hrs contain ubiquitin-binding domains that function in receptor endocytosis

➦   Maintenance of replication forks and the S-phase checkpoint by Cdc18p and Orp1p

➦   ROCK and Dia have opposing effects on adherens junctions downstream of Rho

➦   Hrs sorts ubiquitinated proteins into clathrin-coated microdomains of early endosomes

➦   Morgue mediates apoptosis in the Drosophila melanogaster retina by promoting degradation of DIAP1

➦   Hid, Rpr and Grim negatively regulate DIAP1 levels through distinct mechanisms

➦   Reaper eliminates IAP proteins through stimulated IAP degradation and generalized translational inhi

➦   The DIAP1 RING finger mediates ubiquitination of Dronc and is indispensable for regulating apoptosis

➦   The ZP domain is a conserved module for polymerization of extracellular proteins

➦   Regulation of Drosophila IAP1 degradation and apoptosis by reaper and ubcD1

➦   A novel PKC-regulated mechanism controls CD44–ezrin association and directional cell motility

➦   Drosophila Morgue is an F box/ubiquitin conjugase domain protein important for grim-reaper mediated

➦   The Vps27p–Hse1p complex binds ubiquitin and mediates endosomal protein sorting

➦   p53 stability and activity is regulated by Mdm2-mediated induction of alternative p53 translation pr

➦   The systemic movement of a tobamovirus is inhibited by a cadmium-ion-induced glycine-rich protein

➦   Filamin A-interacting protein (FILIP) regulates cortical cell migration out of the ventricular zone

➦   Cajal Body dynamics and association with chromatin are ATP-dependent

➦   Myosin X is a downstream effector of PI(3)K during phagocytosis

➦   The role of NFAT transcription factors in integrin-mediated carcinoma invasion

➦   Nuclear exclusion of Smad2 is a mechanism leading to loss of competence

➦   Lipid products of PI(3)Ks maintain persistent cell polarity and directed motility in neutrophils

➦   Nucleophosmin regulates the stability and transcriptional activity of p53

➦   A PtdInsP3- and Rho GTPase-mediated positive feedback loop regulates neutrophil polarity

➦   Distinct roles for cyclins E and A during DNA replication complex assembly and activation

➦   β-Arrestins regulate a Ral-GDS–Ral effector pathway that mediates cytoskeletal reorganization

➦   Metastasis is driven by sequential elevation of H-ras and Smad2 levels

➦   The epithelial-specific adaptor AP1B mediates post-endocytic recycling to the basolateral membrane

➦   Zebrafish trilobite identifies new roles for Strabismus in gastrulation and neuronal movements

➦   Molecular interpretation of ERK signal duration by immediate early gene products

➦   Unconventional Rac-GEF activity is mediated through the Dock180–ELMO complex

➦   Kinesin I-dependent cortical exclusion restricts pole plasm to the oocyte posterior

➦   CRMP-2 binds to tubulin heterodimers to promote microtubule assembly

➦   Myosin VI is required for E-cadherin-mediated border cell migration

➦   EphrinA1-induced cytoskeletal re-organization requires FAK and p130cas

➦   Tiam1 mediates Ras activation of Rac by a PI(3)K-independent mechanism

➦   Connective-tissue growth factor (CTGF) modulates cell signalling by BMP and TGF-β

➦   An actin nucleation mechanism mediated by Bni1 and Profilin