➦   Mechanistic insights into the alternative translation termination by ArfA and RF2

➦   Structural basis for ArfA–RF2-mediated translation termination on mRNAs lacking stop codons

➦   Structure and regulation of the chromatin remodeller ISWI

➦   Splicing factor 1 modulates dietary restriction and TORC1 pathway longevity in C. elegans

➦   Genome-wide changes in lncRNA, splicing, and regional gene expression patterns in autism

➦   Evidence for a spinon Fermi surface in a triangular-lattice quantum-spin-liquid candidate

➦   A persistent and dynamic East Greenland Ice Sheet over the past 7.5 million years

➦   Gamma frequency entrainment attenuates amyloid load and modifies microglia

➦   Structure of CC chemokine receptor 2 with orthosteric and allosteric antagonists

➦   Targeting metastasis-initiating cells through the fatty acid receptor CD36

➦   Receptor usage dictates HIV-1 restriction by human TRIM5α in dendritic cell subsets

➦   Electric-field-stimulated protein mechanics

➦   High-resolution mapping of global surface water and its long-term changes

➦   A 17-gene stemness score for rapid determination of risk in acute leukaemia

➦   Intracellular allosteric antagonism of the CCR9 receptor

➦   Greenland was nearly ice-free for extended periods during the Pleistocene

➦   Host genome integration and giant virus-induced reactivation of the virophage mavirus

➦   Integrin-YAP/TAZ-JNK cascade mediates atheroprotective effect of unidirectional shear flow

➦   Centennial-scale Holocene climate variations amplified by Antarctic Ice Sheet discharge

➦   A massive, quiescent, population II galaxy at a redshift of 2.1

➦   NLRC3 is an inhibitory sensor of PI3K–mTOR pathways in cancer

➦   mRNA quality control is bypassed for immediate export of stress-responsive transcripts

➦   Mechanism of early dissemination and metastasis in Her2+ mammary cancer

➦   Chemical intervention in plant sugar signalling increases yield and resilience

➦   Correlated fluorescence blinking in two-dimensional semiconductor heterostructures

➦   Early dissemination seeds metastasis in breast cancer

➦   Near-atomic-resolution cryo-EM analysis of the Salmonella T3S injectisome basal body

➦   Structural basis for gating the high-conductance Ca2+-activated K+ channel

➦   Resolved images of a protostellar outflow driven by an extended disk wind

➦   Cryo-EM structure of the open high-conductance Ca2+-activated K+ channel

➦   Accessing non-natural reactivity by irradiating nicotinamide-dependent enzymes with light

➦   The seahorse genome and the evolution of its specialized morphology

➦   Observation of the 1S–2S transition in trapped antihydrogen

➦   Lifespan effects of mitochondrial mutations

➦   In situ structures of the genome and genome-delivery apparatus in a single-stranded RNA virus

➦   Aromatic and antiaromatic ring currents in a molecular nanoring

➦   Identification of an atypical monocyte and committed progenitor involved in fibrosis

➦   Piezo2 senses airway stretch and mediates lung inflation-induced apnoea

➦   Structural basis of an essential interaction between influenza polymerase and Pol II CTD

➦   Spin–orbit-coupled fermions in an optical lattice clock

➦   Reversible methylation of m6Am in the 5′ cap controls mRNA stability

➦   Self-assembly of tetravalent Goldberg polyhedra from 144 small components

➦   XRCC1 mutation is associated with PARP1 hyperactivation and cerebellar ataxia

➦   Reducing phosphorus accumulation in rice grains with an impaired transporter in the node

➦   Structure of a CLC chloride ion channel by cryo-electron microscopy

➦   Epigenome-wide association study of body mass index, and the adverse outcomes of adiposity

➦   New CRISPR–Cas systems from uncultivated microbes

➦   Evolution of the global phosphorus cycle

➦   Variable chromatin structure revealed by in situ spatially correlated DNA cleavage mapping

➦   Genetic variants regulating expression levels and isoform diversity during embryogenesis