➦   The role of Drosophila CID in kinetochore formation, cell-cycle progression and heterochromatin inte

➦   Reproducible but dynamic positioning of DNA in chromosomes during mitosis

➦   Valosin-containing protein is a multi-ubiquitin chain-targeting factor required in ubiquitin–proteas

➦   Nicastrin binds to membrane-tethered Notch

➦   The Eps15 C. elegans homologue EHS-1 is implicated in synaptic vesicle recycling

➦   Orchestrating anaphase and mitotic exit: separase cleavage and localization of Slk19

➦   Oncogenes in Ras signalling pathway dictate host-cell permissiveness to herpes simplex virus 1

➦   ErbB2, but not ErbB1, reinitiates proliferation and induces luminal repopulation in epithelial acini

➦   Pin1 regulates turnover and subcellular localization of β-catenin by inhibiting its interaction with

➦   Isolation of multipotent adult stem cells from the dermis of mammalian skin

➦   Nuclear localization of EGF receptor and its potential new role as a transcription factor

➦   UDP–sugar transporter implicated in glycosylation and processing of Notch

➦   Dual role of the fringe connection gene in both heparan sulphate and fringe-dependent signalling eve

➦   A nuclear lamin is required for cytoplasmic organization and egg polarity in Drosophila

➦   Four-dimensional imaging and quantitative reconstruction to analyse complex spatiotemporal processes

➦   Enteropathogenic E. coli Tir binds Nck to initiate actin pedestal formation in host cells

➦   Heat-shock protein 70 antagonizes apoptosis-inducing factor

➦   Desmosomal adhesion regulates epithelial morphogenesis and cell positioning

➦   Rac1 orientates epithelial apical polarity through effects on basolateral laminin assembly

➦   Borg proteins control septin organization and are negatively regulated by Cdc42

➦   Checkpoint activation in response to double-strand breaks requires the Mre11/Rad50/Xrs2 complex

➦   A flavoprotein oxidase defines a new endoplasmic reticulum pathway for biosynthetic disulphide bond

➦   Endogenous nitric oxide mechanisms mediate the stretch dependence of Ca2+ release in cardiomyocytes

➦   Endoplasmic reticulum chaperone gp96 is required for innate immunity but not cell viability

➦   Spatial control of the actin cytoskeleton in Drosophila epithelial cells

➦   Drosophila APC2 and Armadillo participate in tethering mitotic spindles to cortical actin

➦   N-WASP deficiency reveals distinct pathways for cell surface projections and microbial actin-based m

➦   Dynein binds to β-catenin and may tether microtubules at adherens junctions

➦   Endocytic protein intersectin-l regulates actin assembly via Cdc42 and N-WASP

➦   Three-dimensional reconstruction of dynamin in the constricted state

➦   Extracellular control of cell size

➦   Acyl-coenzyme A: cholesterol acyltransferase modulates the generation of the amyloid β-peptide

➦   Proteins containing the UBA domain are able to bind to multi-ubiquitin chains

➦   Timing of cyclin D1 expression within G1 phase is controlled by Rho

➦   A multiprotein complex mediates the ATP-dependent assembly of spliceosomal U snRNPs

➦   Mrc1 channels the DNA replication arrest signal to checkpoint kinase Cds1

➦   Mediation of IGF-1-induced skeletal myotube hypertrophy by PI(3)K/Akt/mTOR and PI(3)K/Akt/GSK3 pathw

➦   Cooperative regulation of AJM-1 controls junctional integrity in Caenorhabditis elegans epithelia

➦   Mrc1 transduces signals of DNA replication stress to activate Rad53

➦   Kinesin-dependent movement on microtubules precedes actin-based motility of vaccinia virus

➦   HER-2/neu induces p53 ubiquitination via Akt-mediated MDM2 phosphorylation

➦   Endogenous β-amyloid production in presenilin-deficient embryonic mouse fibroblasts

➦   Loss of SM-B myosin affects muscle shortening velocity and maximal force development

➦   A new phospholipase-C–calcium signalling pathway mediated by cyclic AMP and a Rap GTPase

➦   Akt/mTOR pathway is a crucial regulator of skeletal muscle hypertrophy and can prevent muscle atroph

➦   Regulation of microglial expression of integrins by poly(ADP-ribose) polymerase-1

➦   Kinetochore dynein: its dynamics and role in the transport of the Rough deal checkpoint protein

➦   A mammalian Partner of inscuteable binds NuMA and regulates mitotic spindle organization

➦   Increased filamin binding to β-integrin cytoplasmic domains inhibits cell migration

➦   Feedback regulation of the MBF transcription factor by cyclin Cig2