➦   TGFβ influences Myc, Miz-1 and Smad to control the CDK inhibitor p15INK4b

➦   Substeps within the 8-nm step of the ATPase cycle of single kinesin molecules

➦   Polo kinase and Asp are needed to promote the mitotic organizing activity of centrosomes

➦   Mutations in the APC tumour suppressor gene cause chromosomal instability

➦   A role for the Adenomatous Polyposis Coli protein in chromosome segregation

➦   Stabilization of p53 by p14ARF without relocation of MDM2 to the nucleolus

➦   Regulation of the PH-domain-containing tyrosine kinase Etk by focal adhesion kinase through the FERM

➦   Force and focal adhesion assembly: a close relationship studied using elastic micropatterned substra

➦   ERK induces p35, a neuron-specific activator of Cdk5, through induction of Egr1

➦   WIP regulates N-WASP-mediated actin polymerization and filopodium formation

➦   Tyrosine-phosphorylated SOCS-3 inhibits STAT activation but binds to p120 RasGAP and activates Ras

➦   Activation of EphA receptor tyrosine kinase inhibits the Ras/MAPK pathway

➦   PDGF-D is a specific, protease-activated ligand for the PDGF β-receptor

➦   PDGF-D, a new protease-activated growth factor

➦   Trp2 regulates entry of Ca2+ into mouse sperm triggered by egg ZP3

➦   A 'hot-spot' mutation alters the mechanical properties of keratin filament networks

➦   Fission yeast Bub1 is essential in setting up the meiotic pattern of chromosome segregation

➦   Regulation of transport of the dopamine D1 receptor by a new membrane-associated ER protein

➦   New protease inhibitors prevent γ-secretase-mediated production of Aβ40/42 without affecting Notch c

➦   Dynamics of the COPII coat with GTP and stable analogues

➦   Caveolar endocytosis of simian virus 40 reveals a new two-step vesicular-transport pathway to the ER

➦   Actin dynamics at pointed ends regulates thin filament length in striated muscle

➦   Drosophila Pin1 prolyl isomerase Dodo is a MAP kinase signal responder during oogenesis

➦   Regulation of c-myc expression by PDGF through Rho GTPases

➦   Apaf-1 is a transcriptional target for E2F and p53

➦   Rme-1 regulates the distribution and function of the endocytic recycling compartment in mammalian ce

➦   Evidence that RME-1, a conserved C. elegans EH-domain protein, functions in endocytic recycling

➦   Expression of α- and β-globin genes occurs within different nuclear domains in haemopoietic cells

➦   Direct, high-resolution measurement of furrow stiffening during division of adherent cells

➦   TGF-β induces assembly of a Smad2–Smurf2 ubiquitin ligase complex that targets SnoN for degradation

➦   FGF receptor signalling is required to maintain neural progenitors during Hensen's node progression

➦   Phox domain interaction with PtdIns(3)P targets the Vam7 t-SNARE to vacuole membranes

➦   The translational inhibitor 4E-BP is an effector of PI(3)K/Akt signalling and cell growth in Drosoph

➦   PAR-1 is a Dishevelled-associated kinase and a positive regulator of Wnt signalling

➦   Msps/XMAP215 interacts with the centrosomal protein D-TACC to regulate microtubule behaviour

➦   N-CAM modulates tumour-cell adhesion to matrix by inducing FGF-receptor signalling

➦   Msps protein is localized to acentrosomal poles to ensure bipolarity of Drosophila meiotic spindles

➦   SNX3 regulates endosomal function through its PX-domain-mediated interaction with PtdIns(3)P

➦   Mec1p regulates Pds1p levels in S phase: complex coordination of DNA replication and mitosis

➦   The PX domains of p47phox and p40phox bind to lipid products of PI(3)K

➦   PtdIns(3)P regulates the neutrophil oxidase complex by binding to the PX domain of p40phox

➦   Novel mechanism of Wnt signalling inhibition mediated by Dickkopf-1 interaction with LRP6/Arrow

➦   Yeast Eps15-like endocytic protein, Pan1p, activates the Arp2/3 complex

➦   SV2 modulates the size of the readily releasable pool of secretory vesicles

➦   Acetylation control of the retinoblastoma tumour-suppressor protein

➦   ActA and human zyxin harbour Arp2/3-independent actin-polymerization activity

➦   TGF-β-induced apoptosis is mediated by the adapter protein Daxx that facilitates JNK activation

➦   mDia mediates Rho-regulated formation and orientation of stable microtubules

➦   Triggering ubiquitination of a CDK inhibitor at origins of DNA replication

➦   Mammalian STAG3 is a cohesin specific to sister chromatid arms in meiosis I