➦   The transcription factor Snail controls epithelial–mesenchymal transitions by repressing E-cadherin

➦   Specific interference with gene function by double-stranded RNA in early mouse development

➦   Plasticity in mouse neural crest cells reveals a new patterning role for cranial mesoderm

➦   The transcription factor Snail is a repressor of E-cadherin gene expression in epithelial tumour cel

➦   Defects in pathfinding by cranial neural crest cells in mice lacking the neuregulin receptor ErbB4

➦   DNA-replication/DNA-damage-dependent centrosome inactivation in Drosophila embryos

➦   A conserved docking motif in MAP kinases common to substrates, activators and regulators

➦   Nuclear sequestration of the exchange factor Cdc24 by Far1 regulates cell polarity during yeast mati

➦   Rapid initiation of Arabidopsis pollination requires the oleosin-domain protein GRP17

➦   Kinesin and dynamin are required for post-Golgi transport of a plasma-membrane protein

➦   Rapid movement of axonal neurofilaments interrupted by prolonged pauses

➦   CED-2/CrkII and CED-10/Rac control phagocytosis and cell migration in Caenorhabditis elegans

➦   p16INK4A and p19ARF act in overlapping pathways in cellular immortalization

➦   Ras is involved in nerve-activity-dependent regulation of muscle genes

➦   HIV-1 Nef protein binds to the cellular protein PACS-1 to downregulate class I major histocompatibil

➦   The coordinate release of cytochrome c during apoptosis is rapid, complete and kinetically invariant

➦   Calmodulin kinase determines calcium-dependent facilitation of L-type calcium channels

➦   Identification of a cryptic nucleolar-localization signal in MDM2

➦   Mitotic stability of an episomal vector containing a human scaffold/matrix-attached region is provid

➦   Single-molecule imaging of EGFR signalling on the surface of living cells

➦   The molecular motor dynein is involved in targeting Swallow and bicoid RNA to the anterior pole of

➦   Dynamics and segregation of cell–matrix adhesions in cultured fibroblasts

➦   Presenilin-1 differentially facilitates endoproteolysis of the β-amyloid precursor protein and Notch

➦   Real-time measurements of vesicle-SNARE recycling in synapses of the central nervous system

➦   Noelin-1 is a secreted glycoprotein involved in generation of the neural crest

➦   A new ABC transporter mediating the detachment of lipid-modified proteins from membranes

➦   Regulation of E2F transcription by cyclin E–Cdk2 kinase mediated through p300/CBP co-activators

➦   A new self-assembled peroxisomal vesicle required for efficient resealing of the plasma membrane

➦   Detection of S-phase cells in tissue sections by in situ DNA replication

➦   Involvement of the Arp2/3 complex in phagocytosis mediated by FcγR or CR3

➦   FAK integrates growth-factor and integrin signals to promote cell migration

➦   TRAIL receptor-2 signals apoptosis through FADD and caspase-8

➦   The EAST protein of Drosophila controls an expandable nuclear endoskeleton

➦   Kinesin’s IAK tail domain inhibits initial microtubule-stimulated ADP release

➦   Motor proteins regulate force interactions between microtubules and microfilaments in the axon

➦   Sphingosylphosphorylcholine is a ligand for ovarian cancer G-protein-coupled receptor 1

➦   The TSC1 tumour suppressor hamartin regulates cell adhesion through ERM proteins and the GTPase Rho

➦   Dynamics and retention of misfolded proteins in native ER membranes

➦   Phospholipase C and termination of G-protein-mediated signalling in vivo

➦   PDGF-C is a new protease-activated ligand for the PDGF α-receptor

➦   Changes in intramitochondrial and cytosolic pH: early events that modulate caspase activation during

➦   Gli regulation by the opposing activities of Fused and Suppressor of Fused

➦   Dynamic interaction of BiP and ER stress transducers in the unfolded-protein response

➦   Discrete interactions in cell adhesion measured by single-molecule force spectroscopy

➦   Nitric oxide upregulates expression of DNA-PKcs to protect cells from DNA-damaging anti-tumour agent

➦   Cargo binding and regulatory sites in the tail of fungal conventional kinesin

➦   A new function for the γ -tubulin ring complex as a microtubule minus-end cap

➦   Tollip, a new component of the IL-1RI pathway, links IRAK to the IL-1 receptor

➦   Structure of the γ-tubulin ring complex: a template for microtubule nucleation

➦   Immunostructural evidence for the template mechanism of microtubule nucleation