➦ DNA damage-induced G2–M checkpoint activation by histone H2AX and 53BP1
➦ Pointed and Tramtrack69 establish an EGFR-dependent transcriptional switch to regulate mitosis
➦ Bicaudal-D regulates COPI-independent Golgi–ER transport by recruiting the dynein–dynactin motor com
➦ Myosin IXb is a single-headed minus-end-directed processive motor
➦ Interaction of FANCD2 and NBS1 in the DNA damage response
➦ Yeast epsin-related proteins required for Golgi–endosome traffic define a γ-adaptin ear-binding moti
➦ Unconventional tethering of Ulp1 to the transport channel of the nuclear pore complex by karyopherin
➦ Integrated activity of PDZ protein complexes regulates epithelial polarity
➦ Vimentin is secreted by activated macrophages
➦ Inherent calcineurin inhibitor FKBP38 targets Bcl-2 to mitochondria and inhibits apoptosis
➦ Interactions between the crumbs, lethal giant larvae and bazooka pathways in epithelial polarization
➦ Signalling and crosstalk of Rho GTPases in mediating axon guidance
➦ Regulation of microtubule stability by the von Hippel-Lindau tumour suppressor protein pVHL
➦ ɛ-Tubulin is required for centriole duplication and microtubule organization
➦ The Drosophila HOAP protein is required for telomere capping
➦ Fas engagement induces neurite growth through ERK activation and p35 upregulation
➦ Active cyclin B1–Cdk1 first appears on centrosomes in prophase
➦ Three-dimensional analysis of post-Golgi carrier exocytosis in epithelial cells
➦ Repeated phosphopeptide motifs in Claspin mediate the regulated binding of Chk1
➦ SAP couples Fyn to SLAM immune receptors
➦ Dlg, Scrib and Lgl regulate neuroblast cell size and mitotic spindle asymmetry
➦ Binding of SAP SH2 domain to FynT SH3 domain reveals a novel mechanism of receptor signalling in imm
➦ Direct interaction of two polarity complexes implicated in epithelial tight junction assembly
➦ Native Myosin-IXb is a plus-, not a minus-end-directed motor
➦ The signal flow and motor response controling chemotaxis of sea urchin sperm
➦ A Ran signalling pathway mediated by the mitotic kinase Aurora A in spindle assembly
➦ RhoD regulates endosome dynamics through Diaphanous-related Formin and Src tyrosine kinase
➦ Distinct spatiotemporal dynamics of mammalian checkpoint regulators induced by DNA damage
➦ Reversible disassembly of somatic nucleoli by the germ cell proteins FRGY2a and FRGY2b
➦ A non-proteolytic function of separase links the onset of anaphase to mitotic exit
➦ p53RDL1 regulates p53-dependent apoptosis
➦ Mutated APC and Asef are involved in the migration of colorectal tumour cells
➦ Spontaneous receptor-independent heterotrimeric G-protein signalling in an RGS mutant
➦ Redox-dependent downregulation of Rho by Rac
➦ Cytokines suppress adipogenesis and PPAR-γ function through the TAK1/TAB1/NIK cascade
➦ A polarity complex of mPar-6 and atypical PKC binds, phosphorylates and regulates mammalian Lgl
➦ The spindle-associated transmembrane protein Axs identifies a membranous structure ensheathing the m
➦ Identification of the ubiquitin–protein ligase that recognizes oxidized IRP2
➦ Building a cell cycle oscillator: hysteresis and bistability in the activation of Cdc2
➦ Human CENP-I specifies localization of CENP-F, MAD1 and MAD2 to kinetochores and is essential for mi
➦ PKCε is a permissive link in integrin-dependent IFN-γ signalling that facilitates JAK phosphorylatio
➦ A new link between the c-Abl tyrosine kinase and phosphoinositide signalling through PLC-γ1
➦ Islet β-cell secretion determines glucagon release from neighbouring α-cells
➦ Cytoprotective membrane-permeable peptides designed from the Bax-binding domain of Ku70
➦ Ku70 suppresses the apoptotic translocation of Bax to mitochondria
➦ Reconstitution of γ-secretase activity
➦ Exocytosis of single chromaffin granules in cell-free inside-out membrane patches
➦ Regulation of calcium signals in the nucleus by a nucleoplasmic reticulum
➦ Degradation of DIAP1 by the N-end rule pathway is essential for regulating apoptosis
➦ Translokin is an intracellular mediator of FGF-2 trafficking