➦   Abl-dependent tyrosine phosphorylation of Sos-1 mediates growth-factor-induced Rac activation
➦   Transduction peptides: from technology to physiology
➦   Kinetochore fibre dynamics outside the context of the spindle during anaphase
➦   A signalling pathway controlling c-Myc degradation that impacts oncogenic transformation of human ce
➦   Dynamin 2 binds γ-tubulin and participates in centrosome cohesion
➦   Gating of CFTR by the STAS domain of SLC26 transporters
➦   SREBPs suppress IRS-2-mediated insulin signalling in the liver
➦   Delivery of raft-associated, GPI-anchored proteins to the apical surface of polarized MDCK cells by
➦   PKB/Akt modulates TGF-β signalling through a direct interaction with Smad3
➦   Role of the PAR-3–KIF3 complex in the establishment of neuronal polarity
➦   Abi1 is essential for the formation and activation of a WAVE2 signalling complex
➦   Egalitarian binds dynein light chain to establish oocyte polarity and maintain oocyte fate
➦   Akt interacts directly with Smad3 to regulate the sensitivity to TGF-β-induced apoptosis
➦   Mitochondrial p53 activates Bak and causes disruption of a Bak–Mcl1 complex
➦   Targeting of the Arf-like GTPase Arl3p to the Golgi requires N-terminal acetylation and the membrane
➦   FAPPs control Golgi-to-cell-surface membrane traffic by binding to ARF and PtdIns(4)P
➦   Golgi targeting of ARF-like GTPase Arl3p requires its Nα-acetylation and the integral membrane prote
➦   PtdIns(3,4,5)P3 binding is necessary for WAVE2-induced formation of lamellipodia
➦   Amplitude control of cell-cycle waves by nuclear import
➦   An epididymis-specific β-defensin is important for the initiation of sperm maturation
➦   In vivo self-renewing divisions of haematopoietic stem cells are increased in the absence of the ear
➦   The endogenous ligand Stunted of the GPCR Methuselah extends lifespan in Drosophila
➦   Hematopoietic stem cells convert into liver cells within days without fusion
➦   Cohesin SMC1β is required for meiotic chromosome dynamics, sister chromatid cohesion and DNA recombi
➦   Mechanical stress activates angiotensin II type 1 receptor without the involvement of angiotensin II
➦   Myosin-X provides a motor-based link between integrins and the cytoskeleton
➦   Functional proteomic screens reveal an essential extracellular role for hsp90α in cancer cell invasi
➦   Hes binding to STAT3 mediates crosstalk between Notch and JAK–STAT signalling
➦   Memo mediates ErbB2-driven cell motility
➦   HIF activation by pH-dependent nucleolar sequestration of VHL
➦   PTOP interacts with POT1 and regulates its localization to telomeres
➦   A NUDEL-dependent mechanism of neurofilament assembly regulates the integrity of CNS neurons
➦   PML regulates p53 stability by sequestering Mdm2 to the nucleolus
➦   Pygopus and Legless target Armadillo/β-catenin to the nucleus to enable its transcriptional co-activ
➦   Proteolysis-independent regulation of the transcription factor Met4 by a single Lys 48-linked ubiqui
➦   ATR and ATM regulate the timing of DNA replication origin firing
➦   LATS1 tumour suppressor affects cytokinesis by inhibiting LIMK1
➦   Centriolar SAS-5 is required for centrosome duplication in C. elegans
➦   Phosphorylation of the enteropathogenic E. coli receptor by the Src-family kinase c-Fyn triggers act
➦   Functional role of the AAA peroxins in dislocation of the cycling PTS1 receptor back to the cytosol
➦   SMYD3 encodes a histone methyltransferase involved in the proliferation of cancer cells
➦   Specification of a DNA replication origin by a transcription complex
➦   The mammalian retromer regulates transcytosis of the polymeric immunoglobulin receptor
➦   Dicer is essential for formation of the heterochromatin structure in vertebrate cells
➦   The CDC-14 phosphatase controls developmental cell-cycle arrest in C. elegans
➦   RGM and its receptor neogenin regulate neuronal survival
➦   Rapid vesicular translocation and insertion of TRP channels
➦   Neogenin mediates the action of repulsive guidance molecule
➦   The neurotrophin-receptor-related protein NRH1 is essential for convergent extension movements
➦   Apollon ubiquitinates SMAC and caspase-9, and has an essential cytoprotection function