➦   MLK3 is required for mitogen activation of B-Raf, ERK and cell proliferation

➦   Yeast centrin Cdc31 is linked to the nuclear mRNA export machinery

➦   Centrosome-associated Chk1 prevents premature activation of cyclin-B–Cdk1 kinase

➦   EB1 and APC bind to mDia to stabilize microtubules downstream of Rho and promote cell migration

➦   Dynactin is involved in a checkpoint to monitor cell wall synthesis in Saccharomyces cerevisiae

➦   Control of vesicle fusion by a tyrosine phosphatase

➦   Dysregulation of HSG triggers vascular proliferative disorders

➦   Evidence for a size-sensing mechanism in animal cells

➦   The anaphase promoting complex/cyclosome is recruited to centromeres by the spindle assembly checkpo

➦   Syntabulin is a microtubule-associated protein implicated in syntaxin transport in neurons

➦   Homologue recognition during meiosis is associated with a change in chromatin conformation

➦   Calpain-mediated proteolysis of talin regulates adhesion dynamics

➦   A new effector pathway links ATM kinase with the DNA damage response

➦   Dual regulation of Snail by GSK-3β-mediated phosphorylation in control of epithelial–mesenchymal tra

➦   Hog1 mediates cell-cycle arrest in G1 phase by the dual targeting of Sic1

➦   DNA demethylation is necessary for the epigenetic reprogramming of somatic cell nuclei

➦   Identification of BRCA1-IRIS, a BRCA1 locus product

➦   Recruitment of Xenopus Scc2 and cohesin to chromatin requires the pre-replication complex

➦   Targeted ubiquitination of CDT1 by the DDB1–CUL4A–ROC1 ligase in response to DNA damage

➦   Synaptobrevin is essential for fast synaptic-vesicle endocytosis

➦   Mammalian TOR complex 2 controls the actin cytoskeleton and is rapamycin insensitive

➦   Actin is part of pre-initiation complexes and is necessary for transcription by RNA polymerase II

➦   Two anterograde intraflagellar transport motors cooperate to build sensory cilia on C. elegans neuro

➦   Nitric oxide induces coupling of mitochondrial signalling with the endoplasmic reticulum stress resp

➦   Secretory traffic triggers the formation of tubular continuities across Golgi sub-compartments

➦   A conserved Mis12 centromere complex is linked to heterochromatic HP1 and outer kinetochore protein

➦   Mapping the dynamic organization of the nuclear pore complex inside single living cells

➦   A dermal niche for multipotent adult skin-derived precursor cells

➦   Sorting signals can direct receptor-mediated export of soluble proteins into COPII vesicles

➦   Cytoplasmic ubiquitin ligase KPC regulates proteolysis of p27Kip1 at G1 phase

➦   Organization of a sterol-rich membrane domain by cdc15p during cytokinesis in fission yeast

➦   Rab27A-binding protein Slp2-a is required for peripheral melanosome distribution and elongated cell

➦   The Williams syndrome transcription factor interacts with PCNA to target chromatin remodelling by IS

➦   Guidance of myocardial patterning in cardiac development by Sema6D reverse signalling

➦   Non-canonical Wnt signals are modulated by the Kaiso transcriptional repressor and p120-catenin

➦   Eps8 controls actin-based motility by capping the barbed ends of actin filaments

➦   Nuclear actin and myosin I are required for RNA polymerase I transcription

➦   Role of Bcl-2 family proteins in a non-apoptotic programmed cell death dependent on autophagy genes

➦   A novel actin barbed-end-capping activity in EPS-8 regulates apical morphogenesis in intestinal cell

➦   Chronophin, a novel HAD-type serine protein phosphatase, regulates cofilin-dependent actin dynamics

➦   Intra-nuclear microtubules and a mitotic spindle orientation checkpoint

➦   Akt and 14-3-3η regulate Miz1 to control cell-cycle arrest after DNA damage

➦   Coupling of ER exit to microtubules through direct interaction of COPII with dynactin

➦   IAPs are functionally non-equivalent and regulate effector caspases through distinct mechanisms

➦   A critical role for Cyclin E in cell fate determination in the central nervous system of Drosophila

➦   Impaired permeability to Ins(1,4,5)P3 in a mutant connexin underlies recessive hereditary deafness

➦   Negative regulation of EGFR signalling through integrin-α1β1-mediated activation of protein tyrosine

➦   The human mitotic checkpoint protein BubR1 regulates chromosome–spindle attachments

➦   Drosophila CLASP is required for the incorporation of microtubule subunits into fluxing kinetochore

➦   p53 induces differentiation of mouse embryonic stem cells by suppressing Nanog expression