➦   Drosophila Smoothened phosphorylation sites essential for Hedgehog signal transduction
➦   Myosin-XVa is required for tip localization of whirlin and differential elongation of hair-cell ster
➦   Bcl-2 expression suppresses mismatch repair activity through inhibition of E2F transcriptional activ
➦   Basic mechanism of three-dimensional collagen fibre transport by fibroblasts
➦   FoxM1 is required for execution of the mitotic programme and chromosome stability
➦   SAS-6 defines a protein family required for centrosome duplication in C. elegans and in human cells
➦   Negative cell-cycle regulators cooperatively control self-renewal and differentiation of haematopoie
➦   TRPC1 forms the stretch-activated cation channel in vertebrate cells
➦   OASIS, a CREB/ATF-family member, modulates UPR signalling in astrocytes
➦   JNK phosphorylation of 14-3-3 proteins regulates nuclear targeting of c-Abl in the apoptotic respons
➦   The cell-cycle checkpoint kinase Chk1 is required for mammalian homologous recombination repair
➦   Par-3 controls tight junction assembly through the Rac exchange factor Tiam1
➦   Phosphoregulation of Arp2/3-dependent actin assembly during receptor-mediated endocytosis
➦   Functionally distinct kinesin-13 family members cooperate to regulate microtubule dynamics during in
➦   c-Myc binds to human ribosomal DNA and stimulates transcription of rRNA genes by RNA polymerase I
➦   c-Myc associates with ribosomal DNA and activates RNA polymerase I transcription
➦   Atrophy of S6K1−/− skeletal muscle cells reveals distinct mTOR effectors for cell cycle and size con
➦   Maintenance of the diacylglycerol level in the Golgi apparatus by the Nir2 protein is critical for G
➦   Myc-dependent regulation of ribosomal RNA synthesis during Drosophila development
➦   PAR-6–PAR-3 mediates Cdc42-induced Rac activation through the Rac GEFs STEF/Tiam1
➦   Cdc42–MRCK and Rho–ROCK signalling cooperate in myosin phosphorylation and cell invasion
➦   Role of the RB1 family in stabilizing histone methylation at constitutive heterochromatin
➦   Imaging of single light-responsive clock cells reveals fluctuating free-running periods
➦   Wnt signalling induces maturation of Paneth cells in intestinal crypts
➦   Plant formin AtFH5 is an evolutionarily conserved actin nucleator involved in cytokinesis
➦   Stat3-induced apoptosis requires a molecular switch in PI(3)K subunit composition
➦   Golgi-localized GAP for Cdc42 functions downstream of ARF1 to control Arp2/3 complex and F-actin dyn
➦   Prediction and validation of the distinct dynamics of transient and sustained ERK activation
➦   An α4 integrin–paxillin–Arf-GAP complex restricts Rac activation to the leading edge of migrating ce
➦   SMC5 and SMC6 genes are required for the segregation of repetitive chromosome regions
➦   Regulation of PTEN by Rho small GTPases
➦   Spinophilin regulates Ca2+ signalling by binding the N-terminal domain of RGS2 and the third intrace
➦   CSN facilitates Cullin–RING ubiquitin ligase function by counteracting autocatalytic adapter instabi
➦   Actin and Arf1-dependent recruitment of a cortactin–dynamin complex to the Golgi regulates post-Golg
➦   Active intranuclear movement of herpesvirus capsids
➦   APC is a component of an organizing template for cortical microtubule networks
➦   EphrinB–EphB signalling regulates clathrin-mediated endocytosis through tyrosine phosphorylation of
➦   The KIF3 motor transports N-cadherin and organizes the developing neuroepithelium
➦   Suppression of HIV-1 infection by a small molecule inhibitor of the ATM kinase
➦   Integrin-independent repression of cadherin transcription by talin during axis formation in Drosophi
➦   Uncontrolled calcium sparks act as a dystrophic signal for mammalian skeletal muscle
➦   Sensitized RNAi screen of human kinases and phosphatases identifies new regulators of apoptosis and
➦   Odf2-deficient mother centrioles lack distal/subdistal appendages and the ability to generate primar
➦   Prediction of preadipocyte differentiation by gene expression reveals role of insulin receptor subst
➦   CtBP3/BARS drives membrane fission in dynamin-independent transport pathways
➦   Microtubule-induced focal adhesion disassembly is mediated by dynamin and focal adhesion kinase
➦   Caenorhabditis elegans RME-6 is a novel regulator of RAB-5 at the clathrin-coated pit
➦   Argonaute 2/RISC resides in sites of mammalian mRNA decay known as cytoplasmic bodies
➦   The golgin Lava lamp mediates dynein-based Golgi movements during Drosophila cellularization
➦   The Diaphanous-related formin dDia2 is required for the formation and maintenance of filopodia