➦   Thiourea-catalysed ring opening of episulfonium ions with indole derivatives by means of stabilizing

➦   Amyloid β-sheet mimics that antagonize protein aggregation and reduce amyloid toxicity

➦   Alteration of the oxygen-dependent reactivity of de novo Due Ferri proteins

➦   Three-way switching in a cyanide-bridged [CoFe] chain

➦   Synthesis of highly strained terpenes by non-stop tail-to-head polycyclization

➦   Selectivity and direct visualization of carbon dioxide and sulfur dioxide in a decorated porous host

➦   Submicrometre geometrically encoded fluorescent barcodes self-assembled from DNA

➦   Engaging unactivated alkyl, alkenyl and aryl iodides in visible-light-mediated free radical reaction

➦   Control of selectivity in heterogeneous catalysis by tuning nanoparticle properties and reactor resi

➦   Prebiotic synthesis of simple sugars by photoredox systems chemistry

➦   Combinatorial evolution of site- and enantioselective catalysts for polyene epoxidation

➦   Hidden complexity in the isomerization dynamics of Holliday junctions

➦   RNA catalysis through compartmentalization

➦   An N-bridged high-valent diiron–oxo species on a porphyrin platform that can oxidize methane

➦   Molecular engineering of a cobalt-based electrocatalytic nanomaterial for H2 evolution under fully a

➦   Ammonia synthesis using a stable electride as an electron donor and reversible hydrogen store

➦   Twin disulfides for orthogonal disulfide pairing and the directed folding of multicyclic peptides

➦   Shape-selective sieving layers on an oxide catalyst surface

➦   Electronic tuning of site-selectivity

➦   Inelastic scattering of hydroxyl radicals with helium and argon by velocity-map imaging

➦   Halogen-bonding-triggered supramolecular gel formation

➦   Uranium and manganese assembled in a wheel-shaped nanoscale single-molecule magnet with high spin-re

➦   Stability of xenon oxides at high pressures

➦   Submolecular control, spectroscopy and imaging of bond-selective chemistry in single functionalized

➦   Extreme oxatriquinanes and a record C–O bond length

➦   A flow-system array for the discovery and scale up of inorganic clusters

➦   A ‘clusters-in-liquid’ method for calculating infrared spectra identifies the proton-transfer mode i

➦   Synthesis of a metallic mesoporous pyrochlore as a catalyst for lithium–O2 batteries

➦   Regioselective reactions of 3,4-pyridynes enabled by the aryne distortion model

➦   Synthetic cascades are enabled by combining biocatalysts with artificial metalloenzymes

➦   Natural-product-derived fragments for fragment-based ligand discovery

➦   Real-time and in situ monitoring of mechanochemical milling reactions

➦   Bond-strengthening π backdonation in a transition-metal π-diborene complex

➦   Protonation-coupled redox reactions in planar antiaromatic meso-pentafluorophenyl-substituted o-phen

➦   A divergent approach to the synthesis of the yohimbinoid alkaloids venenatine and alstovenine

➦   Sulfur as a selective ‘soft’ oxidant for catalytic methane conversion probed by experiment and theor

➦   A near-infrared fluorophore for live-cell super-resolution microscopy of cellular proteins

➦   A backbone lever-arm effect enhances polymer mechanochemistry

➦   A supramolecular approach to combining enzymatic and transition metal catalysis

➦   Catalytic transformation of alcohols to carboxylic acid salts and H2 using water as the oxygen atom

➦   A ring-distortion strategy to construct stereochemically complex and structurally diverse compounds

➦   Molecular shape sorting using molecular organic cages

➦   Quantitative visualization of DNA G-quadruplex structures in human cells

➦   A sustainable catalytic pyrrole synthesis

➦   Volume-conserving trans–cis isomerization pathways in photoactive yellow protein visualized by picos

➦   Snapshot of the equilibrium dynamics of a drug bound to HIV-1 reverse transcriptase

➦   Phase-transfer-catalysed asymmetric synthesis of tetrasubstituted allenes

➦   A spray-drying strategy for synthesis of nanoscale metal–organic frameworks and their assembly into

➦   A heparin-mimicking polymer conjugate stabilizes basic fibroblast growth factor

➦   Molecular tweezers modulate 14-3-3 protein–protein interactions