➦   A distinct role for Lgr5+ stem cells in primary and metastatic colon cancer

➦   DHX9 suppresses RNA processing defects originating from the Alu invasion of the human genome

➦   Transboundary health impacts of transported global air pollution and international trade

➦   Mapping of a non-spatial dimension by the hippocampal–entorhinal circuit

➦   A low-spin Fe(iii) complex with 100-ps ligand-to-metal charge transfer photoluminescence

➦   Groundwater depletion embedded in international food trade

➦   Mutual regulation of tumour vessel normalization and immunostimulatory reprogramming

➦   A retrograde co-orbital asteroid of Jupiter

➦   Catch shares slow the race to fish

➦   Predicting crystal growth via a unified kinetic three-dimensional partition model

➦   Myt1l safeguards neuronal identity by actively repressing many non-neuronal fates

➦   Mono-unsaturated fatty acids link H3K4me3 modifiers to C. elegans lifespan

➦   Structural basis for selectivity and diversity in angiotensin II receptors

➦   Re-evaluation of learned information in Drosophila

➦   A massive, quiescent galaxy at a redshift of 3.717

➦   Dual-phase nanostructuring as a route to high-strength magnesium alloys

➦   Large historical growth in global terrestrial gross primary production

➦   Background-free search for neutrinoless double-β decay of 76Ge with GERDA

➦   Ultrastrong steel via minimal lattice misfit and high-density nanoprecipitation

➦   T-cell invigoration to tumour burden ratio associated with anti-PD-1 response

➦   Therapeutic reduction of ataxin-2 extends lifespan and reduces pathology in TDP-43 mice

➦   Antisense oligonucleotide therapy for spinocerebellar ataxia type 2

➦   Topological defects control collective dynamics in neural progenitor cell cultures

➦   Virus genomes reveal factors that spread and sustained the Ebola epidemic

➦   The earliest bird-line archosaurs and the assembly of the dinosaur body plan

➦   Observation of the frozen charge of a Kondo resonance

➦   Rad51-mediated double-strand break repair and mismatch correction of divergent substrates

➦   High-avidity IgA protects the intestine by enchaining growing bacteria

➦   Finding pathways to national-scale land-sector sustainability

➦   Human knockouts and phenotypic analysis in a cohort with a high rate of consanguinity

➦   The crown-of-thorns starfish genome as a guide for biocontrol of this coral reef pest

➦   Topological defects in epithelia govern cell death and extrusion

➦   Observed quantization of anyonic heat flow

➦   A living mesoscopic cellular automaton made of skin scales

➦   Mechanism of chromatin remodelling revealed by the Snf2-nucleosome structure

➦   Visualizing multistep elevator-like transitions of a nucleoside transporter

➦   Cohesin is positioned in mammalian genomes by transcription, CTCF and Wapl

➦   Human umbilical cord plasma proteins revitalize hippocampal function in aged mice

➦   Super-multiplex vibrational imaging

➦   Decarboxylative alkenylation

➦   The genetic basis of parental care evolution in monogamous mice

➦   SLAMF7 is critical for phagocytosis of haematopoietic tumour cells via Mac-1 integrin

➦   Antarctic ice shelf potentially stabilized by export of meltwater in surface river

➦   Structure and allosteric inhibition of excitatory amino acid transporter 1

➦   A temperate rocky super-Earth transiting a nearby cool star

➦   Drivers of salamander extirpation mediated by Batrachochytrium salamandrivorans

➦   Modulating the therapeutic response of tumours to dietary serine and glycine starvation

➦   Widespread movement of meltwater onto and across Antarctic ice shelves

➦   Remote epitaxy through graphene enables two-dimensional material-based layer transfer

➦   Three-dimensional printing of transparent fused silica glass