➦ Tracing the origins of relapse in acute myeloid leukaemia to stem cells
➦ mTORC1-dependent AMD1 regulation sustains polyamine metabolism in prostate cancer
➦ Making waves in a photoactive polymer film
➦ On-chip generation of high-dimensional entangled quantum states and their coherent control
➦ Is there evidence for a limit to human lifespan?
➦ Maximum human lifespan may increase to 125 years
➦ Many possible maximum lifespan trajectories
➦ Questionable evidence for a limit to human lifespan
➦ Contesting the evidence for limited human lifespan
➦ Pre-oral gut contributes to facial structures in non-teleost fishes
➦ The pyrite-type high-pressure form of FeOOH
➦ Transcription elongation factors represent in vivo cancer dependencies in glioblastoma
➦ Cryo-EM structures of tau filaments from Alzheimer’s disease
➦ Nutrient sensing modulates malaria parasite virulence
➦ Crystal structures of agonist-bound human cannabinoid receptor CB1
➦ An immunogenic personal neoantigen vaccine for patients with melanoma
➦ Dependency of a therapy-resistant state of cancer cells on a lipid peroxidase pathway
➦ Three-dimensional integration of nanotechnologies for computing and data storage on a single chip
➦ Personalized RNA mutanome vaccines mobilize poly-specific therapeutic immunity against cancer
➦ Episodic kinematics in continental rifts modulated by changes in mantle melt fraction
➦ Cryo-EM structure of the protein-conducting ERAD channel Hrd1 in complex with Hrd3
➦ Cell-cycle dynamics of chromosomal organization at single-cell resolution
➦ West Antarctic Ice Sheet retreat driven by Holocene warm water incursions
➦ Upholding a role for EMT in pancreatic cancer metastasis
➦ Upholding a role for EMT in breast cancer metastasis
➦ Large-scale physical activity data reveal worldwide activity inequality
➦ A novel mechanism for mechanosensory-based rheotaxis in larval zebrafish
➦ K2P2.1 (TREK-1)–activator complexes reveal a cryptic selectivity filter binding site
➦ Synaptic organization of visual space in primary visual cortex
➦ Open and closed structures reveal allostery and pliability in the HIV-1 envelope spike
➦ Infant viewing of social scenes is under genetic control and is atypical in autism
➦ CRISPR–Cas encoding of a digital movie into the genomes of a population of living bacteria
➦ TFH-derived dopamine accelerates productive synapses in germinal centres
➦ Cholangiocytes act as facultative liver stem cells during impaired hepatocyte regeneration
➦ Quantum back-action-evading measurement of motion in a negative mass reference frame
➦ Allelic reprogramming of 3D chromatin architecture during early mammalian development
➦ Conflicting evidence for ferroelectricity
➦ Tundra uptake of atmospheric elemental mercury drives Arctic mercury pollution
➦ Overestimate of committed warming
➦ Visible-light-driven methane formation from CO2 with a molecular iron catalyst
➦ Fructose-1,6-bisphosphate and aldolase mediate glucose sensing by AMPK
➦ Global forest loss disproportionately erodes biodiversity in intact landscapes