➦   A new Drosophila APC homologue associated with adhesive zones of epithelial cells

➦   Haem oxygenase-1 prevents cell death by regulating cellular iron

➦   Noggin is a mesenchymally derived stimulator of hair-follicle induction

➦   Translocation of a calcium-permeable cation channel induced by insulin-like growth factor-I

➦   Crystal structure of the amino-terminal domain of N-ethylmaleimide-sensitive fusion protein

➦   Post-transcriptional regulation of the meiotic Cdc25 protein Twine by the Dazl orthologue Boule

➦   Activation of inwardly rectifying K+ channels by distinct PtdIns(4,5)P2 interactions

➦   A new internal-ribosome-entry-site motif potentiates XIAP- mediated cytoprotection

➦   SKP2 is required for ubiquitin-mediated degradation of the CDK inhibitor p27

➦   Selective regulation of integrin–cytoskeleton interactions by the tyrosine kinase Src

➦   p45SKP2 promotes p27Kip1 degradation and induces S phase in quiescent cells

➦   Role for α-dystrobrevin in the pathogenesis of dystrophin-dependent muscular dystrophies

➦   Apoptosis overrides survival signals through a caspase-mediated dominant-negative NF-κB loop

➦   The base of the proteasome regulatory particle exhibits chaperone-like activity

➦   Yeast homologue of neuronal frequenin is a regulator of phosphatidylinositol-4-OH kinase

➦   Rac regulates phosphorylation of the myosin-II heavy chain, actinomyosin disassembly and cell spread

➦   Phosphatidylinositol-3-OH kinases are Rab5 effectors

➦   Activation of LIM-kinase by Pak1 couples Rac/Cdc42 GTPase signalling to actin cytoskeletal dynamics

➦   Mice lacking Smad3 show accelerated wound healing and an impaired local inflammatory response

➦   Dark is a Drosophila homologue of Apaf-1/CED-4 and functions in an evolutionarily conserved death pa

➦   The receptor for the orexigenic peptide melanin-concentrating hormone is a G-protein-coupled recepto

➦   ARF mediates recruitment of PtdIns-4-OH kinase-β and stimulates synthesis of PtdIns(4,5)P2 on the Go

➦   Kinesin’s tail domain is an inhibitory regulator of the motor domain

➦   Crosstalk between cAMP-dependent kinase and MAP kinase through a protein tyrosine phosphatase

➦   The dynamin-related GTPase Dnm1 regulates mitochondrial fission in yeast