➦   A ubiquitin-selective AAA-ATPase mediates transcriptional switching by remodelling a repressor–promo

➦   The EMT-activator ZEB1 promotes tumorigenicity by repressing stemness-inhibiting microRNAs

➦   Cell fate decisions are specified by the dynamic ERK interactome

➦   M-Sec promotes membrane nanotube formation by interacting with Ral and the exocyst complex

➦   YAP-dependent induction of amphiregulin identifies a non-cell-autonomous component of the Hippo path

➦   Sec24b selectively sorts Vangl2 to regulate planar cell polarity during neural tube closure

➦   Rab27a and Rab27b control different steps of the exosome secretion pathway

➦   An actomyosin-based barrier inhibits cell mixing at compartmental boundaries in Drosophila embryos

➦   A bacterial E3 ubiquitin ligase IpaH9.8 targets NEMO/IKKγ to dampen the host NF-κB-mediated inflamma

➦   Cdk2 suppresses cellular senescence induced by the c-myc oncogene

➦   Carbonic anhydrases are upstream regulators of CO2-controlled stomatal movements in guard cells

➦   Defects in DNA ligase I trigger PCNA ubiquitylation at Lys 107

➦   A role for Rho GTPases and cell–cell adhesion in single-cell motility in vivo

➦   Orphan nuclear receptor TLX activates Wnt/β-catenin signalling to stimulate neural stem cell prolife

➦   Maintenance of a constitutive heterochromatin domain in vertebrates by a Dicer-dependent mechanism

➦   GM1 structure determines SV40-induced membrane invagination and infection

➦   HERC2 coordinates ubiquitin-dependent assembly of DNA repair factors on damaged chromosomes

➦   The Machado-Joseph disease deubiquitylase ATX-3 couples longevity and proteostasis

➦   Single-molecule transcript counting of stem-cell markers in the mouse intestine

➦   Puma and p21 represent cooperating checkpoints limiting self-renewal and chromosomal instability of

➦   Autophagic targeting of Src promotes cancer cell survival following reduced FAK signalling

➦   Polarized cell growth in Arabidopsis requires endosomal recycling mediated by GBF1-related ARF excha

➦   Reprogramming of the tumour microenvironment by stromal PTEN-regulated miR-320

➦   The GDI-like solubilizing factor PDEδ sustains the spatial organization and signalling of Ras family

➦   A ciliopathy complex at the transition zone protects the cilia as a privileged membrane domain