➦   Telomere-independent Rap1 is an IKK adaptor and regulates NF-κB-dependent gene expression
➦   Mammalian Rap1 controls telomere function and gene expression through binding to telomeric and extra
➦   Positive feedback between p53 and TRF2 during telomere-damage signalling and cellular senescence
➦   The PIAS homologue Siz2 regulates perinuclear telomere position and telomerase activity in budding y
➦   DNA-damage response and repair activities at uncapped telomeres depend on RNF8
➦   Telomeric DNA damage is irreparable and causes persistent DNA-damage-response activation