Presenilins are required for γ-secretase cleavage of β-APP and transmembrane cleavage of Notch-1

Author:  ["Zhuohua Zhang","Philip Nadeau","Weihong Song","Dorit Donoviel","Menglan Yuan","Alan Bernstein","Bruce A. Yankner"]

Publication:  Nature Cell Biology

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Tags:  general   CellBiology   CancerResearch   DevelopmentalBiology   StemCells   Biological

Abstract


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Zhang, Z., Nadeau, P., Song, W. et al. Presenilins are required for γ-secretase cleavage of β-APP and transmembrane cleavage of Notch-1. Nat Cell Biol 2, 463–465 (2000). https://doi.org/10.1038/35017108

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>> Full Text:   Presenilins are required for γ-secretase cleavage of β-APP and transmembrane cleavage of Notch-1

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