Author: ["Maria Cuozzo","Keith M. O'Connell","Wojciech Kaniewski","Rong-Xiang Fang","Nam-Hai Chua","Nilgun E. Tumer"]
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Abstract
Progeny of transgenic tobacco plants expressing the cucumber mosaic virus (CMV) coat protein (CP +) or its antisense transcript (antisense–CP) were protected from CMV infection. Symptom development and virus accumulation were reduced or absent in CP+ plants, independent of the strength of the inoculum. Antisense–CP plants were protected only at low inoculum concentrations. These results demonstrate that although it is possible to obtain protection in transgenic plants using antisense–CP message, this protection is not as effective as the CP–mediated protection.Cite this article
Cuozzo, M., O'Connell, K., Kaniewski, W. et al. Viral Protection in Transgenic Tobacco Plants Expressing the Cucumber Mosaic Virus Coat Protein or its Antisense RNA. Nat Biotechnol 6, 549–557 (1988). https://doi.org/10.1038/nbt0588-549 