➦   Smooth-muscle contraction without smooth-muscle myosin

➦   Latrunculin alters the actin-monomer subunit interface to prevent polymerization

➦   A regulatory link between ER-associated protein degradation and the unfolded-protein response.

➦   The Arp2/3 complex branches filament barbed ends: functional antagonism with capping proteins

➦   ABC1 promotes engulfment of apoptotic cells and transbilayer redistribution of phosphatidylserine.

➦   Intercellular communication mediated by the extracellular calcium-sensing receptor

➦   LET-413 is a basolateral protein required for the assembly of adherens junctions in Caenorhabditis e

➦   ERBIN: a basolateral PDZ protein that interacts with the mammalian ERBB2/HER2 receptor

➦   Transition-state analogue inhibitors of γ-secretase bind directly to presenilin-1

➦   Modulation of retinoid signalling through NGF-induced nuclear export of NGFI-B

➦   Ubiquitination of hypoxia-inducible factor requires direct binding to the β-domain of the von Hippel

➦   A complex of N-WASP and WIP integrates signalling cascades that lead to actin polymerization

➦   Targeting to rhoptry organelles of Toxoplasma gondii involves evolutionarily conserved mechanisms.

➦   A Drosophila melanogaster homologue of Caenorhabditis elegans par-1 acts at an early step in embryon

➦   Calcium-dependent modulation by melatonin of the circadian rhythm in malarial parasites.

➦   Total inactivation of γ–secretase activity in presenilin-deficient embryonic stem cells

➦   Presenilins are required for γ-secretase cleavage of β-APP and transmembrane cleavage of Notch-1

➦   Heat-shock protein 70 inhibits apoptosis by preventing recruitment of procaspase-9 to the Apaf-1 apo

➦   Negative regulation of the Apaf-1 apoptosome by Hsp70

➦   CENP-E forms a link between attachment of spindle microtubules to kinetochores and the mitotic check

➦   Cohesin ensures bipolar attachment of microtubules to sister centromeres and resists their precociou

➦   Formation of the male-specific muscle in female Drosophila by ectopic fruitless expression

➦   Receptor-mediated hydrolysis of plasma membrane messenger PIP2 leads to K+-current desensitization

➦   The cell-polarity protein Par6 links Par3 and atypical protein kinase C to Cdc42

➦   A mammalian PAR-3–PAR-6 complex implicated in Cdc42/Rac1 and aPKC signalling and cell polarity