Keyhole coherent diffractive imaging
Author: ["Brian Abbey","Keith A. Nugent","Garth J. Williams","Jesse N. Clark","Andrew G. Peele","Mark A. Pfeifer","Martin de Jonge","Ian McNulty"]
Publication: Nature Physics
CITE.CC academic search helps you expand the influence of your papers.
Abstract
A powerful coherent diffractive X-ray imaging technique could enable next generation synchrotrons and free-electron lasers to study much larger samples than previously thought possible. The availability of third-generation synchrotrons and ultimately X-ray free-electron lasers1 is driving the development of many new methods of microscopy. Among these techniques, coherent diffractive imaging (CDI) is one of the most promising, offering nanometre-scale imaging of non-crystallographic samples. Image reconstruction from a single diffraction pattern has hitherto been possible only for small, isolated samples, presenting a fundamental limitation on the CDI method. Here we report on a form of imaging we term ‘keyhole’ CDI, which can reconstruct objects of arbitrary size. We demonstrate the technique using visible light and X-rays, with the latter producing images of part of an extended object with a detector-limited resolution of better than 20 nm. Combining the improved resolution of modern X-ray optics with the wavelength-limited resolution of CDI, the method paves the way for detailed imaging of a single quantum dot or of a small virus within a complex host environment.
Cite this article
Abbey, B., Nugent, K., Williams, G. et al. Keyhole coherent diffractive imaging. Nature Phys 4, 394–398 (2008). https://doi.org/10.1038/nphys896
