➦   Targeting gene expression to hypoxic tumor cells

➦   Sunlight and skin cancer: Inhibition of p53 mutations in UV-irradiated mouse skin by sunscreens

➦   Protection of chimpanzees from high-dose heterologous HIV-1 challenge by DNA vaccination

➦   Induction of antitumor activity by immunization with fusions of dendritic and carcinoma cells

➦   Bioactivation of leukotoxins to their toxic diols by epoxide hydrolase

➦   The emb operon, a gene cluster of Mycobacterium tuberculosis involved in resistance to ethambutol

➦   Urinary bladder-urethral sphincter dysfunction in mice with targeted disruption of neuronal nitric o

➦   Maternal HIV-1 viral load and vertical transmission of infection: The Ariel Project for the preventi

➦   Empirical evidence for the severe but localized impact of AIDS on population structure

➦   A homologue of Drosophila tissue polarity gene frizzled is expressed in migrating myofibroblasts in

➦   Estrogen inhibits the vascular injury response in estrogen receptor α-deficient mice

➦   ONYX-015, an E1B gene-attenuated adenovirus, causes tumor-specific cytolysis and antitumoral efficac

➦   Long-term protection of chimpanzees against high-dose HIV-1 challenge induced by immunization

➦   Restoration of the growth suppression function of mutant p53 by a synthetic peptide derived from the

➦   Flt3 ligand induces tumor regression and antitumor immune responses in vivo

➦   Novel retinoid-related molecules as apoptosis inducers and effectve inhibitors of human lung cancer

➦   Prophylaxis against HIV-1 infection in chimpanzees by nevirapine, a nonnucleoside inhibitor of rever

➦   Monocyte deactivation in septic patients: Restoration by IFN-γ treatment

➦   Monoclonal antibodies against the 4-1BB T-cell activation molecule eradicate established tumors

➦   Enx (Hox11L1)-deficient mice develop myenteric neuronal hyperplasia and megacolon

➦   Detection of bladder cancer recurrence by microsatellite analysis of urine

➦   Globus pallidus stimulation activates the cortical motor system during alleviation of parkinsonian s

➦   Retinoic acid treatment abrogates elastase-induced pulmonary emphysema in rats

➦   Adenoviral gene transfer of ciliary neurotrophic factor and brain-derived neurotrophic factor leads

➦   Human CD4+ cells transfected with IL-16 cDNA are resistant to HIV-1 infection: Inhibition of mRNA ex

➦   Induction of basal cell carcinoma features in transgenic human skin expressing Sonic Hedgehog

➦   Human acute myeloid leukemia is organized as a hierarchy that originates from a primitive hematopoie

➦   Heritable disorder resembling neuronal storage disease in mice expressing prion protein with deletio

➦   Identification of tissue transglutaminase as the autoantigen of celiac disease

➦   High plasma HDL concentrations associated with enhanced atherosclerosis in transgenic mice overexpre

➦   Induction of high levels of allogeneic hematopoietic reconstitution and donor-specific tolerance wit

➦   Activation of cAMP–PKA signaling in vivo inhibits smooth muscle cell proliferation induced by vascul

➦   Fas ligand expression in islets of Langerhans does not confer immune privilege and instead targets t

➦   Powerful inhibition of kainic acid seizures by neuropeptide Y via Y5-like receptors

➦   Decreased lysosomal storage in the adult MPS VII mouse brain in the vicinity of grafts of retroviral

➦   Disruption of monolayer integrity enables activation of a cystic fibrosis “bypass” channel in human

➦   Mapping pathophysiological features of breast tumors by MRI at high spatial resolution

➦   Transgenic plants expressing autoantigens fed to mice to induce oral immune tolerance

➦   Hyperaccumulation of FAD-linked presenilin 1 variants in vivo

➦   Reciprocal relation between VEGF and NO in the regulation of endothelial integrity

➦   Antisense targeting of basic fibroblast growth factor and dibroblast growth factor receptor-1 in hum

➦   Immunostimulatory DNA sequences function as T helper-1-promoting adjuvants

➦   In vivo transfection of cis element “decoy” against nuclear factor- κB binding site prevents myocard

➦   Simian virus-40 large-T antigen binds p53 in human mesotheliomas

➦   Inhibition of the alloantibody response by CD95 ligand

➦   Dengue virus infectivity depends on envelope protein binding to target cell heparan sulfate

➦   Zinc alters conformation and inhibits biological activities of nerve growth factor and related neuro

➦   A novel anti-apoptosis gene, survivin, expressed in cancer and lymphoma

➦   Association of simian immunodeficiency virus Nef with cellular serine/threonine kinases is dispensab

➦   Amyloid deposition is delayed in mice with targeted deletion of the serum amyloid P component gene