➦   Isolation of novel virus-like sequences associated with human hepatitis

➦   Preclinical efficacy of a prototype DNA vaccine: Enhanced protection against antigenic drift in infl

➦   γδ T cell-induced nitric oxide production enhances resistance to mucosal candidiasis

➦   Inhibition of cellular ras prevents smooth muscle cell proliferation after vascular injury in vivo

➦   Clotrimazole inhibits cell proliferation in vitro and in vivo

➦   A single-injection protein kinase A-directed antisense treatment to inhibit tumour growth

➦   Chemical generation of nitric oxide in the mouth from the enterosalivary circulation of dietary nitr

➦   5′ CpG island methylation is associated with transcriptional silencing of the tumour suppressor p16/

➦   The drug resistance-related protein LRP is the human major vault protein

➦   Non-enzymatically glycated tau in Alzheimer's disease induces neuronal oxidant stress resulting in c

➦   Failure of T-cell homeostasis preceding AIDS in HIV-1 infection

➦   Intracellular expression of antibody fragments directed against HIV reverse transcriptase prevents H

➦   Effects of the MYC oncogene antagonist, MAD, on proliferation, cell cycling and the malignant phenot

➦   Targeting antigen into the phagocytic pathway in vivo induces protective tumour immunity

➦   The emergence of a highly transmissible lineage of cbl+ Pseudomonas (Burkholderia) cepacia causing C

➦   Altered striatal dopamine re-uptake site densities in habitually violent and non-violent alcoholics

➦   Brain stem activation in spontaneous human migraine attacks

➦   Neutralization of HIV-1 by secretory IgA induced by oral immunization with a new macromolecular mult

➦   Prevention of breast tumour development in vivo by downregulation of the p185neureceptor

➦   A role for a new herpes virus (KSHV) in different forms of Kaposi's sarcoma

➦   Protection against bronchial asthma by CFTR ΔF508 mutation: A heterozygote advantage in cystic fibro

➦   Serum p53 antibodies as early markers of lung cancer

➦   The feasibility of targeted selective gene therapy of the hair follicle

➦   The biological effects of endogenous nerve growth factor on adult sensory neurons revealed by a trkA

➦   Marfan syndrome as a paradigm for transcript-targeted preimplantation diagnosis of heterozygous muta

➦   Are there separate central nervous system pathways for touch and pain?

➦   Enzyme-independent formation of nitric oxide in biological tissues

➦   Spectacle lenses alter eye growth and the refractive status of young monkeys

➦   The intrinsic transmission dynamics of tuberculosis epidemics

➦   Spatial and temporal control of gene therapy using ionizing radiation

➦   Inhibition of farnesyltransferase induces regression of mammary and salivary carcinomas in ras trans

➦   The limit of human adaptation to starvation

➦   Tumour suppression by the human von Hippel-Lindau gene product

➦   Evidence of an X-linked or recessive genetic component to prostate cancer risk

➦   Decreased α-secretase-cleaved amyloid precursor protein as a diagnostic marker for Alzheimer's disea

➦   CD26 expression correlates with entry, replication and cytopathicity of monocytotropic HIV–1 strains

➦   Marked amelioration of established collagen-induced arthritis by treatment with antibodies to CD23 i

➦   Attenuated multi–mutated herpes simplex virus–1 for the treatment of malignant gliomas

➦   Identification of endothelin–1 in the pathophysiology of metastatic adenocarcinoma of the prostate

➦   Microallelotyping defines the sequence and tempo of alleiic losses at tumour suppressor gene loci du

➦   The antisense homology box: A new motif within proteins that encodes biologically active peptides

➦   Overexpression of the obese (ob) gene in adipose tissue of human obese subjects

➦   Resistance of microorganisms to disinfection in dental and medical devices

➦   Recombinant IL–12 prevents formation of blocking IgA antibodies to recombinant adenovirus and allows

➦   Release and activation of platelet latent TGF–β in blood clots during dissolution with plasmin

➦   Long–term protection against SIV–induced disease in macaques vaccinated with a live attenuated HIV–2

➦   Increased obese mRNA expression in omental fat cells from massively obese humans

➦   A picornaviral protein synthesized out of frame with the polyprotein plays a key role in a virus–ind

➦   Stimulation in the human somatosensory thalamus can reproduce both the affective and sensory dimensi

➦   Identification of a novel dual angiotensin II/vasopressin receptor on the basis of molecular recogni