➦   Interspecies organogenesis generates autologous functional islets

➦   Molybdenum chloride catalysts for Z-selective olefin metathesis reactions

➦   Prevalence and architecture of de novo mutations in developmental disorders

➦   Elevation alters ecosystem properties across temperate treelines globally

➦   Plasmodium malariae and P. ovale genomes provide insights into malaria parasite evolution

➦   Dermatologist-level classification of skin cancer with deep neural networks

➦   Force interacts with macromolecular structure in activation of TGF-β

➦   A competitive inhibitory circuit for selection of active and passive fear responses

➦   A solution to the single-question crowd wisdom problem

➦   Symmetry-protected collisions between strongly interacting photons

➦   The isotopic nature of the Earth’s accreting material through time

➦   PLD3 gene and processing of APP

➦   Vigorous lateral export of the meltwater outflow from beneath an Antarctic ice shelf

➦   Ruthenium isotopic evidence for an inner Solar System origin of the late veneer

➦   Ecosystem restoration strengthens pollination network resilience and function

➦   Identity and dynamics of mammary stem cells during branching morphogenesis

➦   Gamma oscillations organize top-down signalling to hypothalamus and enable food seeking

➦   Meiofaunal deuterostomes from the basal Cambrian of Shaanxi (China)

➦   Molecular mechanism for the regulation of yeast separase by securin

➦   Deciphering chemical order/disorder and material properties at the single-atom level

➦   Rare and low-frequency coding variants alter human adult height

➦   Newly born peroxisomes are a hybrid of mitochondrial and ER-derived pre-peroxisomes

➦   Mega-evolutionary dynamics of the adaptive radiation of birds

➦   Feedback control of AHR signalling regulates intestinal immunity

➦   Zika virus protection by a single low-dose nucleoside-modified mRNA vaccination

➦   Pathologically expanded peripheral T helper cell subset drives B cells in rheumatoid arthritis

➦   Single-cell spatial reconstruction reveals global division of labour in the mammalian liver

➦   Primordial helium entrained by the hottest mantle plumes

➦   Ancestral morphology of crown-group molluscs revealed by a new Ordovician stem aculiferan

➦   Onset of the aerobic nitrogen cycle during the Great Oxidation Event

➦   Synthetic vulnerabilities of mesenchymal subpopulations in pancreatic cancer

➦   Synthetic essentiality of chromatin remodelling factor CHD1 in PTEN-deficient cancer

➦   The genome of Chenopodium quinoa

➦   EPRS is a critical mTORC1–S6K1 effector that influences adiposity in mice

➦   Extrachromosomal oncogene amplification drives tumour evolution and genetic heterogeneity

➦   C. elegans neurons jettison protein aggregates and mitochondria under neurotoxic stress

➦   Photovoltage field-effect transistors

➦   Inhibition decorrelates visual feature representations in the inner retina

➦   An intermediate-mass black hole in the centre of the globular cluster 47 Tucanae

➦   Recent increase in oceanic carbon uptake driven by weaker upper-ocean overturning

➦   Metabolic gatekeeper function of B-lymphoid transcription factors

➦   m6A-dependent maternal mRNA clearance facilitates zebrafish maternal-to-zygotic transition

➦   SZT2 dictates GATOR control of mTORC1 signalling

➦   Static non-reciprocity in mechanical metamaterials

➦   Phosphatidylinositol 3-kinase δ blockade increases genomic instability in B cells

➦   Sterile protection against human malaria by chemoattenuated PfSPZ vaccine

➦   KICSTOR recruits GATOR1 to the lysosome and is necessary for nutrients to regulate mTORC1

➦   Untimely expression of gametogenic genes in vegetative cells causes uniparental disomy

➦   Mechanical stretch triggers rapid epithelial cell division through Piezo1

➦   Whole-genome landscape of pancreatic neuroendocrine tumours